During DNA replication, which enzyme removes RNA primers?

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Multiple Choice

During DNA replication, which enzyme removes RNA primers?

Explanation:
Primers are RNA segments that start DNA synthesis, and they must be removed and replaced with DNA to make a continuous strand. RNase H specifically targets RNA in RNA-DNA hybrids, cleaving that RNA so the primer can be removed. After the primer is erased, DNA polymerase fills the gap with DNA, and DNA ligase seals the final nick. The other enzymes don’t remove RNA primers—helicase unwinds DNA, DNA polymerase builds new DNA, and ligase seals nicks after synthesis.

Primers are RNA segments that start DNA synthesis, and they must be removed and replaced with DNA to make a continuous strand. RNase H specifically targets RNA in RNA-DNA hybrids, cleaving that RNA so the primer can be removed. After the primer is erased, DNA polymerase fills the gap with DNA, and DNA ligase seals the final nick. The other enzymes don’t remove RNA primers—helicase unwinds DNA, DNA polymerase builds new DNA, and ligase seals nicks after synthesis.

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